What is the TULSA Procedure?


The TULSA Procedure, also known as transurethral ultrasound ablation, is a minimally invasive treatment used to ablate targeted prostate tissue. 

Performed in an MRI suite using the TULSA-PRO® Transurethral Ultrasound Ablation System, the procedure combines AI-powered robotic assistance, real-time MRI guidance, temperature monitoring and directional ultrasound energy. This allows the treating doctor to plan, monitor and deliver controlled ablation to a defined area of prostate tissue, while aiming to preserve healthy tissue around the treatment area. 

During the procedure, an ultrasound applicator is inserted through the urethra, meaning no surgical incisions are required. The treatment plan can be tailored to your individual anatomy and to the location and amount of prostate tissue being treated. This personalised approach aims to preserve nearby structures involved in urinary and sexual function, both of which are important aspects of overall quality of life.

What to Expect During the TULSA Procedure?

If you are considering the TULSA Procedure, knowing what to expect can help you prepare for your treatment. Your healthcare team will guide you through the process, from preparing for the procedure to your care immediately afterwards.

The procedure generally involves: 

  1. You will be asleep under anaesthesia throughout the procedure. 

  1. A small ultrasound applicator is inserted through the urethra, allowing treatment to be delivered from within the prostate without the need for a surgical incision. 

  1. Real-time MRI imaging allows the treating doctor to view the prostate and guide treatment towards the selected area. 

  1. Directional ultrasound energy heats and ablates the targeted prostate tissue while aiming to preserve healthy tissue around the treatment area. 

  1. The TULSA Procedure is generally performed as a same-day procedure, and patients can usually return home following treatment. Recovery varies between individuals, but the procedure is designed to minimise pain and downtime while supporting quality of life. 

Considering the TULSA Procedure

Every patient’s circumstances are different. The TULSA Procedure may be considered by men seeking a personalised, minimally invasive treatment approach that does not involve traditional prostate surgery.

Your treating doctor can discuss whether the procedure may be suitable for you and explain its potential benefits and other relevant considerations. These may include:

 

  • A treatment plan tailored to your prostate size, shape and disease characteristics 

  • A same-day outpatient procedure that generally does not require an overnight hospital stay 

  • A relatively quick recovery, although recovery times vary between patients¹ 

  • Low rates of serious urinary incontinence and erectile dysfunction reported in the referenced clinical study² 

  • Some patients taking blood-thinning medication may be considered for the procedure following an individual medical assessment 

Reported Outcomes Following the TULSA Procedure 

Understanding how treatment may affect your quality of life is an important part of considering your treatment options.  

Clinical studies of the TULSA Procedure have reported patient outcomes that include the preservation of urinary control and erectile function.¹ These findings can help inform discussions with your treating doctor.  

The TACT clinical study involved 115 men with localised prostate cancer who underwent whole-gland ablation using the TULSA Procedure. The study reported that: 
 

97%
maintained urinary control²

87%
preserved erectile function²


These results reflect the patients included in the study. Individual outcomes may vary, and your treating doctor can explain how these findings may relate to your circumstances. 

TULSA-PRO® Frequently Asked Questions

  • How long does the procedure take?

    The TULSA Procedure generally takes between two and four hours. The length of the procedure depends on the amount of prostate tissue targeted for treatment and your individual treatment plan.

  • What can I expect during recovery?

    Patients generally return home on the day of the procedure. A catheter may be required for several days to help drain the bladder while the prostate begins to heal. 

    Some patients experience tiredness or discomfort during the first few days. Many return to light activities within several days to a week, although recovery varies between individuals. Your treating doctor will advise when you can safely resume work, exercise, travel and sexual activity. 

  • What follow-up will I need?

    Your treating team will monitor your recovery, provide guidance about catheter care and arrange its removal when appropriate. Ongoing monitoring may include blood tests, imaging or other examinations, depending on your individual circumstances. 

    Your doctor will explain your follow-up schedule and how your response to treatment will be assessed. 

  • Does the TULSA Procedure involve a laser?
    No. The TULSA Procedure uses directional ultrasound energy to ablate selected prostate tissue. Real-time MRI guidance is used to monitor and guide the treatment. 
  • What is the success rate of TULSA-PRO?

    Outcomes vary depending on factors such as: 

    • Your disease state 
    • Whether treatment is partial or whole-gland 
    • Your follow-up care 

Could the TULSA Procedure be suitable for me?

Your treating doctor can determine whether the TULSA Procedure may be appropriate for you based on your individual circumstances. 

1Klotz et al, “MRI-guided transurethral ultrasound ablation of prostate cancer,” The Journal of Urology (2021).  

2Eggener et al, “Pivotal Study of MRI-Guided Transurethral Ultrasound Ablation (TULSA) of Localized Prostate Cancer: 5-Year Follow Up” Urol Onc (2024)  

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